Does the blood we thought to know so well contain elements that had been undetectable until now? The answer is yes, according to a team of researchers from Inserm, Université de Montpellier and the Montpellier Cancer Institute ...
Jan 23, 2020
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A key challenge in neuroscience is to understand how the brain can adapt to a changing world, even with a relatively static anatomy. The way the brain's areas are structurally and functionally related to each other—its ...
Jun 19, 2023
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In the brain, neurons communicate via neurotransmitters, which trigger electrical signals in downstream neurons by binding and activating specific receptors. Neurotransmitters are released through the fusion of synaptic vesicles, ...
Jun 6, 2023
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Humans have developed four different IgG antibody subclasses that orchestrate protection against invading pathogens. A molecular and cellular understanding of how these contribute to eradication of viral infections may guide ...
May 2, 2022
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The Granzyme B (GzmB) enzyme, which accumulates in certain tissues as we age, has been identified as a driver of itchy and sometimes life-threatening autoimmune conditions known as pemphigoid diseases (PDs), which cause blistering ...
Jan 13, 2021
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Loss of the "housekeeping" gene methylthioadenosine phosphorylase, or MTAP, is a common event in cancer. Patients with melanoma or bladder cancer whose tumor cells lack a functioning version of the gene tend not to respond ...
Sep 28, 2023
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The permanent neurological deficits of multiple sclerosis patients largely depend on the extent of degeneration of long nerve fibers. The latter is initiated by ruptures in the cell membrane and the resulting influx of calcium ...
Jan 25, 2019
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A reliable sense of space is essential for daily life and memory formation. Removing sugar coated proteins around neurons in the brains' internal gps makes the mental map of space unstable, shows a study published in the ...
Jan 19, 2021
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The brain contains billions of nerve cells controlling our thoughts, behavior and movements. But in fact, up to 20% of the brain is a mystery to scientists. This is the so-called extracellular space, that is, the environment ...
Nov 9, 2023
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A team of researchers, affiliated with UNIST have unraveled the molecular mechanisms behind the activation of multiple inflammasomes and their role in inducing inflammatory cell death. This discovery sheds light on the connection ...
Nov 30, 2023
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