Medical research

Circadian clocks play a key role in fat cell growth

Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies by Weill Cornell Medicine investigators.

Overweight & Obesity

Aldose reductase promotes diet-induced obesity

High-fat diet (HFD) feeding in mice promotes induction of aldose reductase (AR) activity, expression, and senescence of adipocytes in subcutaneous adipose tissue (scAT), according to a new study in Obesity journal.

Overweight & Obesity

Can weekly prednisone treat obesity?

Obese mice that were fed a high-fat diet and that received prednisone one time per week had improved exercise endurance, got stronger, increased their lean body mass and lost weight, reports a new Northwestern Medicine study. ...

Immunology

Immune cells regulate body weight

Obesity is among the biggest health challenges of the 21st century, according to the World Health Organization (WHO). Almost 60% of Germans are considered overweight, while 25% are obese. Moreover, being overweight often ...

Neuroscience

Brain cell's ability to use fat determines weight gain in mice

Like the body itself, cells within the body of living animals require fuel for energy, but it's not always known how different fuel sources affect the function of those cells. Astrocytes, a type of brain cell, for instance, ...

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