Oncology & Cancer

Study shows why many cancer cells need to import fat

Columbia and MIT researchers are revealing the surprising reasons why cancer cells are often forced to rely on fat imports, a finding that could lead to new ways to understand and slow down tumor growth.

Overweight & Obesity

Blood vessel cells implicated in chronic inflammation of obesity

Dec. 30, 2020—When fat cells in the body are stuffed with excess fat, the surrounding tissue becomes inflamed. That chronic, low-level inflammation is one of the driving factors behind many of the diseases associated with ...

Diabetes

Single enzyme is necessary for development of diabetes

An enzyme called 12-LO promotes the obesity-induced oxidative stress in the pancreatic cells that leads to pre-diabetes, and diabetes. 12-LO's enzymatic action is the last step in the production of certain small molecules ...

Diabetes

Insulin-sensitive fat leads to obesity

SORLA is a protein that influences the balance of metabolic processes in adipose tissue, a particular form of fat. Too much of it makes fat cells overly sensitive to insulin, which leads them to break down less fat. SORLA ...

Neuroscience

Enzyme ensures thick insulation

ETH researchers have revealed that Schwann cells in the peripheral nervous system largely produce their own fatty acids in order to create electrical insulation for nerve fibres. This process relies on an enzyme whose absence ...

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