Immunology

Innate immune responses to high-fat diets lead to obesity

Why is eating a high fat diet a recipe for obesity? According to a new study from the RIKEN Center for Integrative Medical Sciences (IMS) in Japan, the answer involves the activity of a specific type of immune cell that lives ...

Medical research

Could coffee be the secret to fighting obesity?

Scientists from the University of Nottingham have discovered that drinking a cup of coffee can stimulate 'brown fat', the body's own fat-fighting defenses, which could be the key to tackling obesity and diabetes.

Gerontology & Geriatrics

How interval training affects 'belly fat' in obese 70-year-olds

By today's estimates, one-third of adults aged 65 or older are obese. This growing obesity trend, along with the decrease in our level of physical activity as we age, seriously raises our risk of diseases and death.

Medications

Bladder drug linked to atherosclerosis in mice

A drug used in the treatment of overactive bladder can accelerate atherosclerosis in mice, researchers at Karolinska Institutet in Sweden report in a study published in the Proceedings of the National Academy of Sciences ...

Medical research

The heart 'talks' to fat cells, scientists discover

Like sending a letter through the mail or a text over a cellular network, the heart can generate messages that travel long distances through the body. Those messages ultimately reach fat cells, new research by scientists ...

Diabetes

How the body protects itself from type 2 diabetes

A specific group of white blood cells, termed "regulatory T cells," keeps the immune system in balance and suppresses its activity to protect the body against autoimmune diseases. Scientists at the German Center for Neurodegenerative ...

Overweight & Obesity

Exercise during pregnancy protects offspring from obesity

A new study found that offspring born to mice that exercised during pregnancy were less likely to gain weight after consuming a high-fat diet later in life. Although previous studies have shown that exercise by obese females ...

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Adipose tissue

In histology, adipose tissue or body fat or just fat is loose connective tissue composed of adipocytes. Adipose tissue is derived from lipoblasts. Its main role is to store energy in the form of fat, although it also cushions and insulates the body. Obesity or being overweight in humans and most animals does not depend on body weight but on the amount of body fat—specifically, adipose tissue. Two types of adipose tissue exist: white adipose tissue (WAT) and brown adipose tissue (BAT). Adipose tissue also serves as an important endocrine organ by producing hormones such as leptin, resistin and the cytokine TNFα. The formation of adipose tissue appears to be controlled by the adipose gene. Adipose tissue was first identified by the Swiss naturalist Conrad Gessner in 1551.\

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