Diabetes

Tiny change has big effects, reverses prediabetes in mice

A small chemical change—shifting the position of two hydrogen atoms—makes the difference between mice that are healthy and mice with insulin resistance and fatty liver, major risk factors for diabetes and heart disease. ...

Gastroenterology

A new path toward microbiome-informed precision nutrition

Short-chain fatty acids (SCFAs) are beneficial molecules created by the bacteria residing in our gut that are closely tied to improved host metabolism, lower systemic inflammation, better cardiovascular health, lower cancer ...

Genetics

Building a blueprint of metabolic health—from mouse to human

Metabolic syndrome (MetS) is a health condition characterized by a group of risk factors: high blood pressure, high blood sugar, unhealthy cholesterol levels, and abdominal fat. These factors increase the risk of heart disease, ...

Overweight & Obesity

New drug candidate reverses obesity in mice

Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells' mitochondria. A study published in Nature Metabolism shows that a specific class of drugs that block ...

Biomedical technology

Researchers use the eye as a window to study liver health

Researchers at Karolinska Institutet have developed a method to study liver function and disease without requiring invasive procedures. After transplanting liver cells into the eye of mice, the cornea can be used as a window ...

page 1 from 30