Diabetes

Tiny change has big effects, reverses prediabetes in mice

A small chemical change—shifting the position of two hydrogen atoms—makes the difference between mice that are healthy and mice with insulin resistance and fatty liver, major risk factors for diabetes and heart disease. ...

Overweight & Obesity

New drug candidate reverses obesity in mice

Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells' mitochondria. A study published in Nature Metabolism shows that a specific class of drugs that block ...

Biomedical technology

Researchers use the eye as a window to study liver health

Researchers at Karolinska Institutet have developed a method to study liver function and disease without requiring invasive procedures. After transplanting liver cells into the eye of mice, the cornea can be used as a window ...

Oncology & Cancer

Study reveals how fatty liver promotes colorectal cancer spread

Investigators at Cedars-Sinai Cancer found that fatty liver, a condition closely associated with obesity, promotes the spread of colorectal cancer to the liver. Their study, published today in the journal Cell Metabolism, ...

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