Inflammatory disorders

Metabolites shed by intestinal microbiota keep inflammation at bay

Researchers at Tufts University have elucidated a mechanism by which the "good" bacteria that reside in our gastrointestinal tract can help protect us from inflammation, and how their disruption (dysbiosis) can increase the ...

Diseases, Conditions, Syndromes

Scientists reverse mechanism of fatty liver disease

Researchers have identified the mechanism which causes a build-up of fat in the liver in a disease affecting one in five in the UK—and were able to reverse it in a mouse model.

Immunology

When liver immune cells turn bad

A high-fat diet and obesity turn "hero" virus-fighting liver immune cells "rogue", leading to insulin resistance, a condition that often results in type 2 diabetes, according to research published today in Science Immunology.

Arthritis & Rheumatism

High-fat, high-carb diet a cause of osteoarthritis

Saturated fat is a prime suspect in the onset of osteoarthritis after QUT scientists found it changed the composition of cartilage, particularly in the weight-bearing joints of the hip and knee.

Medical research

Changes in the diet affect epigenetics via the microbiota

You are what you eat, the old saying goes, but why is that so? Researchers have known for some time that diet affects the balance of microbes in our bodies, but how that translates into an effect on the host has not been ...

Neuroscience

High-fat diet disrupts brain maturation

The latest study by researchers from ETH Zurich and the University of Zurich suggests that excessive consumption of fatty foods could severely disrupt the development of the prefrontal cortex in the maturing brains of young ...

Medical research

Grandpa's obesity affects the health of his grandchildren

With more than 14 million Australians now overweight or obese, researchers are warning of the harmful legacy that parental obesity can have on future generations. It follows a vital breakthrough in obesity research, which ...

Medical research

Brain receptor regulates fat burning in cells

Scientists at the Gladstone Institutes have discovered an unusual regulator of body weight and the metabolic syndrome: a molecular mechanism more commonly associated with brain cells. Lowering levels of P75 neurotrophin receptor ...

Medical research

Link between a mitochondrial defect and heart disease discovered

A defect in a vital mitochondrial process in heart cells causes a type of dilated cardiomyopathy, a heart condition that in humans leads in most cases to heart disease and premature death. The research was undertaken by teams ...

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