Genetics

Memory making involves extensive DNA breaking

The urgency to remember a dangerous experience requires the brain to make a series of potentially dangerous moves: Neurons and other brain cells snap open their DNA in numerous locations—more than previously realized, according ...

Neuroscience

With these neurons, extinguishing fear is its own reward

When you expect a really bad experience to happen and then it doesn't, it's a distinctly positive feeling. A new study of fear extinction training in mice may suggest why: The findings not only identify the exact population ...

Medical research

Unlocking the molecular mechanism of PTSD treatment

Post-traumatic stress disorder (PTSD) is a difficult-to-cure mental health condition that is caused by experiencing a traumatizing event, such as interpersonal violence or disaster. While sufferers of PTSD have existed across ...

Neuroscience

Medial prefrontal cortex linked to fear response

(Medical Xpress)—In a new paper published in the current issue of Neuron, Harvard Medical School researchers at McLean Hospital report that increased activity in the medial prefrontal cortex of the brain is linked to decreased ...

Neuroscience

The neurological basis for fear and memory

Fear conditioning using sound and taste aversion, as applied to mice, have revealed interesting information on the basis of memory allocation.

Psychology & Psychiatry

Epigenetics contribute to male and female differences in fear memory

In a mouse model of traumatic memory, male mice recall fear-related memories better than female mice, according to a study in Biological Psychiatry. The difference between sexes was attributed to a gene important for creating ...

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