A heartbeat is a carefully coordinated series of electrical signals led by sodium ion channels, which tell the heart when to contract and to relax. Any disruption to these signals may lead to cardiac diseases such as an irregular ...
Apr 3, 2023
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Fibroblasts build and maintain the extracellular matrix, or physical scaffolding for cells, in the connective tissues within the body. It is believed that cancerous tumors can recruit nearby fibroblasts and use them to promote ...
Mar 28, 2023
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A Matrix Biology paper by the Werner group (IMHS) shows how wound healing gene expression signatures are expressed in tumors and can be used to predict cancer outcome. The paper establishes a functional link between wound ...
Mar 27, 2023
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Burn wounds are notoriously prone to bacterial infection and typically lead to a larger amount of scar tissue than laceration wounds.
Mar 14, 2023
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The tissue area that surrounds our teeth is known as the gingiva, and healthy teeth will nestle firmly into the gums thanks to the many gingival fibers that connect the tooth to the gingiva. The gingiva is home to fibroblasts—cells ...
Mar 10, 2023
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Researchers from the Indiana Center for Regenerative Medicine and Engineering (ICRME) have identified a new type of cell in the human and mouse body, called the vasculogenic fibroblast, that provides critical insight into ...
Mar 1, 2023
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Lung cancer is the biggest cause of cancer death in the U.K., but a study by a team of scientists from the University of Southampton has discovered a new way to identify patients who are twice as likely to die from the disease.
Feb 1, 2023
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A type of cell that plays a key role in pancreatic cancer can trace its origin back to a structure that forms during embryonic development, new research at MUSC Hollings Cancer Center shows. This new data, published recently ...
Jan 20, 2023
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Interleukin (IL)-11 is produced by inflammatory fibroblasts, one of the stromal cells, during acute colitis. Researchers at Toho University Japan found that IL-11 ameliorated acute colitis in mouse models. The IL-11 production ...
Jan 17, 2023
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Researchers at the University of Colorado School of Medicine have discovered a new mechanism for slowing scarring of heart tissue—a process known as cardiac fibrosis.
Jan 6, 2023
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