Genetics

Genome editing helps decipher a congenital liver disease

Congenital hepatic fibrosis (CHF) is a rare genetic disease that causes malformation and fibrosis (scarring) of the liver. Occurring in roughly one out of every 20,000 births, CHF can lead to an enlarged liver, impaired blood ...

Medical research

Photoacoustic endoscopy could improve Crohn's disease treatment

A newly developed endoscope could give doctors a better view of intestinal changes caused by Crohn's disease. This additional information would help improve treatment of the painful and debilitating form of inflammatory bowel ...

Diseases, Conditions, Syndromes

Scientists report new approach to reduce or prevent renal fibrosis

Renal fibrosis, the abnormal accumulation of fibrotic material within the kidney, hinders kidney function and may lead to eventual renal failure. Using genetically altered mice, researchers from Duke University investigated ...

Diseases, Conditions, Syndromes

Novel biomarkers for noninvasive diagnosis of NAFLD-related fibrosis

With an estimated 25% of people worldwide affected by nonalcoholic fatty liver disease (NAFLD), there is a large unmet need for accurate, noninvasive measures to enhance early diagnosis and screening of hepatic fibrosis. ...

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Fibrosis

Fibrosis is the formation or development of excess fibrous connective tissue in an organ or tissue as a reparative or reactive process, as opposed to a formation of fibrous tissue as a normal constituent of an organ or tissue.

The term is also sometimes used to describe a normal healing process, but this usage is less common.

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