Neuroscience
UTSA professor develops open-access software for cytoskeleton
Researchers around the world now have access to an open-access software designed to further characterize cytoskeleton filaments.
Nov 13, 2020
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News tagged with filament
Neuroscience
New mouse model of tau propagation
Accumulation of assembled tau protein in the central nervous system is characteristic of Alzheimer's disease and several other neurodegenerative diseases, called tauopathies. Recent studies have revealed that propagation ...
Sep 23, 2020
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Medical research
Getting to the heart of heartbeats: Cardiac thin filament structure and function revealed
Researchers at Osaka University used electron cryomicroscopy (CryoEM) to image essential cardiac muscle components, known as thin filaments, with unprecedented resolution. They also discovered the mechanism by which these ...
Jan 9, 2020
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Diseases, Conditions, Syndromes
Researchers determine bacteria structure responsible for traveler's diarrhea
For the first time researchers have deciphered the near-atomic structure of filaments, called 'pili', that extend from the surface of bacteria that cause traveler's diarrhea. Without pili, these bacteria do not cause disease. ...
Jul 10, 2019
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Neuroscience
Scientists discover unique tau filament structures in head-injury associated dementia
Researchers at the MRC Laboratory of Molecular Biology (LMB) have revealed the atomic structures of the abnormal tau filaments associated with chronic traumatic encephalopathy (CTE), a head injury-associated neurodegenerative ...
Mar 21, 2019
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Medical research
Mystery novel and dream spur key scientific insight into heart defect
On Dec. 14, 2014, after many months of not getting expected results, biochemist Jim Spudich got into bed, read a chunk of a novel, fell asleep and had a dream that would change the focus of his entire field in thinking about ...
Mar 21, 2019
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Alzheimer's disease & dementia
Neuronal cytoskeletons involved in Alzheimer's disease
A researcher at the UPV/EHU participated in a study describing the loss of dynamics and subsequent impairment of the dendritic spines in Alzheimer's disease. Dendritic spines are the compartments of neurons responsible for ...
Jan 18, 2019
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Medical research
New insight into the generation of new neurons in the adult brain
Researchers at Sahlgrenska Academy at the University of Gothenburg, Sweden, in collaboration with research groups in Finland, Canada and Slovenia, have discovered a novel and unexpected function of nestin, the best-known ...
Jan 3, 2019
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Oncology & Cancer
Actin cytoskeleton remodeling protects tumor cells against immune attack
Cancer cells have evolved multiple escape strategies to circumvent the body's immune defenses, such as the attack by natural killer (NK) cells that normally kill abnormal cells by releasing cytotoxic products. While studying ...
Oct 24, 2018
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Neuroscience
Structure of tau filaments in patients with Pick's disease determined
A team of researchers with the MRC Laboratory of Molecular Biology in the U.K. and Indiana University School of Medicine in the U.S. has determined the structure of tau filaments in patients with Pick's disease. In their ...
