A new study published in Nature Cardiovascular Research uncovers the crucial role of the AmotL2 protein in connecting mechanical forces to endothelial cell integrity and alignment. This discovery sheds light on junctional ...
Jun 30, 2023
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A team of international researchers led by Northwestern Medicine scientists has identified how a defective protein plays a central role in a rare, lethal childhood disease known as Giant Axonal Neuropathy, or GAN. The finding ...
Apr 29, 2013
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Blocking the formation of filaments—multi-enzyme structures that fuel cancer activity—may offer new ways to control cancer cell proliferation, according to a new study led by Cornell researchers.
Mar 5, 2024
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A study in The Journal of Cell Biology identifies a motor protein that ferries HIV to the plasma membrane, helping the virus escape from macrophages.
Oct 22, 2012
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Neurodegenerative diseases such as Alzheimer's could be better understood thanks to insight into proteins linked to such conditions, a study suggests.
Jul 2, 2013
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Scientists at the University of Manchester have uncovered how the internal mechanisms in nerve cells wire the brain. The findings open up new avenues in the investigation of neurodegenerative diseases by analysing the cellular ...
Jul 20, 2012
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Two hearts, said Keats, can beat as one; but a study led by Weizmann Institute scientists in collaboration with researchers from the University of Pennsylvania shows that sometimes a single heart muscle cell can beat as more ...
Mar 3, 2015
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For the first time, a defective protein that plays a specific role in degrading intermediate filaments (IF), one of three classes of filaments that form the structure of nerve cells, has been discovered by an international ...
Dec 17, 2012
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For the first time researchers have deciphered the near-atomic structure of filaments, called 'pili', that extend from the surface of bacteria that cause traveler's diarrhea. Without pili, these bacteria do not cause disease. ...
Jul 10, 2019
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Researchers around the world now have access to an open-access software designed to further characterize cytoskeleton filaments.
Nov 13, 2020
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