Diseases, Conditions, Syndromes

Researchers bring us one step closer to universal influenza vaccine

The scourge of the influenza virus devastates health and claims many lives worldwide each year. It is especially daunting because vaccines are only protective when they are well matched to the strains circulating in the population. ...

Diseases, Conditions, Syndromes

From parade to pandemic: Museum looks at 1918's deadly flu

On Sept. 28, 1918, in the waning days of World War I, over 200,000 people gathered along Broad Street in Philadelphia for a parade meant to raise funds for the war effort. Among the patriotic throngs cheering for troops and ...

Diseases, Conditions, Syndromes

Towards better hand hygiene for flu prevention

Rubbing hands with ethanol-based sanitizers should provide a formidable defense against infection from flu viruses, which can thrive and spread in saliva and mucus. But findings published this week in mSphere challenge that ...

Pediatrics

Pediatric flu vaccine guidelines updated for 2019-20 season

(HealthDay)—In a policy statement published online Sept. 2 in Pediatrics, updated recommendations are presented regarding influenza vaccines for children, with no preference for any one product or formulation over another.

Diseases, Conditions, Syndromes

Infectious disease A-Z: Will there be a universal flu vaccine?

A better, more effective flu vaccine is a matter of when—not if—says Dr. Gregory Poland, director of Mayo Clinic's Vaccine Research Group. The National Institutes of Health is testing an experimental universal flu vaccine ...

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Orthomyxoviridae

Influenzavirus A Influenzavirus B Influenzavirus C Isavirus Thogotovirus

The Orthomyxoviridae (orthos, Greek for "straight"; myxa, Greek for "mucus") are a family of RNA viruses that includes five genera: Influenzavirus A, Influenzavirus B, Influenzavirus C, Isavirus and Thogotovirus. The first three genera contain viruses that cause influenza in vertebrates, including birds (see also avian influenza), humans, and other mammals. Isaviruses infect salmon; thogotoviruses infect vertebrates and invertebrates, such as mosquitoes and sea lice.

The three genera of Influenzavirus, which are identified by antigenic differences in their nucleoprotein and matrix protein infect vertebrates as follows:

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