Psychology & Psychiatry

The far-reaching effects of antidepressants

When University of Ottawa biologists Marilyn Vera-Chang and Vance Trudeau began to study the effects of a popular antidepressant on reproduction levels in zebrafish, they stumbled across something that changed the course ...

Medications

Should patients stop taking Prozac when pregnant?

Women, and perhaps their doctors, may be concerned when they see reports of a study showing an association between taking fluoxetine, an antidepressant also known as Prozac, during pregnancy and birth defects in children.

Diseases, Conditions, Syndromes

Anti-depressant link to Clostridium difficile infection

Certain types of anti-depressants have been linked to an increase in the risk of Clostridium difficile infection (CDI) finds a study in BioMed Central's open access journal BMC Medicine. Awareness of this link should improve ...

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Fluoxetine

Fluoxetine (also known by the tradenames Prozac, Sarafem, Fontex) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is manufactured and marketed by Eli Lilly and Company. In combination with olanzapine it is known as Symbyax.

Fluoxetine is approved for the treatment of major depression (including pediatric depression), obsessive-compulsive disorder (in both adult and pediatric populations), bulimia nervosa, panic disorder and premenstrual dysphoric disorder.

Despite the availability of newer agents, fluoxetine remains extremely popular. In 2010, over 24.4 million prescriptions for generic formulations of fluoxetine were filled in the United States alone, making it the third most prescribed antidepressant after sertraline (SSRI; became generic in 2006) and citalopram (SSRI; became generic in 2003) in that country.

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