In the wake of recent disappointments over clinical trials targeting amyloid plaque build-up in Alzheimer's disease, researchers are focusing more attention on misfolded tau protein, another culprit in brain diseases that ...
Dec 18, 2019
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Led by professor Ludo Van Den Bosch (VIB-KU Leuven), scientists from Belgium, the UK and the US have identified new processes that form protein "clumps" that are characteristic of amyotrophic lateral sclerosis (ALS) and frontotemporal ...
Mar 17, 2017
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Although the technology has existed for just a few years, scientists increasingly use "disease in a dish" models to study genetic, molecular and cellular defects. But a team of doctors and scientists led by researchers at ...
Oct 25, 2013
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Brain diseases associated with the misformed protein tau, including Alzheimer's disease and frontotemporal lobar degeneration with tau pathologies, are characterized by neurofibrillary tangles (NFTs) comprised of pathological ...
Jan 15, 2013
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Alzheimer's disease and frontotemporal lobar degeneration (FTLD) are two of the most prevalent forms of neurodegenerative disorders. In a study published online today in Genome Research, researchers have analyzed changes ...
Aug 15, 2011
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Expectations for data sharing among scientists and returning research results to study subjects have evolved in recent years. A new study led by a Georgia State University researcher underscores potential barriers to sharing ...
Apr 2, 2024
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Alzheimer's disease researchers at the University of Virginia have discovered how harmful tau proteins damage the essential operating instructions for our brain cells, a finding that could lead to new treatments.
Dec 19, 2023
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Limbic predominate age-related TDP-43 encephalopathy or LATE is a recently recognized form of dementia that affects memory, thinking and social skills. It mimics Alzheimer's disease or AD (and sometimes co-exists with it), ...
Dec 15, 2022
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There is currently no cure for Parkinson's disease (PD), and one of the main difficulties for developing treatments is that we don't know exactly how or why the disease occurs. It's generally believed that a buildup of Lewy ...
Jul 5, 2022
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A test of protein in the blood is receiving further support as a biomarker for patients diagnosed with frontotemporal dementia (FTD), a group of brain disorders with few treatment options. These disorders are characterized ...
Apr 19, 2022
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