Medical research

Novel paradigm in drug development

Traditional medicines mostly function as inhibitors, attacking the disease-relevant proteins that cause cancer, by binding to their accessible pockets. Following this strategy, only ~20% of all proteins are chemically addressable, ...

Oncology & Cancer

Scientists identify genes tied to increased risk of ovarian cancer

A team of researchers at UCLA's Jonsson Comprehensive Cancer, Cedars-Sinai Cancer and Dana-Farber Cancer Institute have newly identified 34 genes that are associated with an increased risk for developing the earliest stages ...

Oncology & Cancer

What Netflix can teach us about treating cancer

Two years ago, former President Barack Obama announced the Precision Medicine initiative in his State of the Union Address. The initiative aspired to a "new era of medicine" where disease treatments could be specifically ...

Neuroscience

Simulating biological thought process within a computer system

The structure of the brain reveals a network of massively interconnected electrochemically active cells. It is known that information can be represented by changes of state within this network, but that statement falls far ...

Genetics

Human immune system shapes skin microbiome

Our skin plays host to millions of beneficial and potentially disease-causing microorganisms; however, whether our immune system influences these microbial communities to prevent disease is unknown. In a study published online ...

Genetics

Wide range of differences, mostly unseen, among humans

No two human beings are the same. Although we all possess the same genes, our genetic code varies in many places. And since genes provide the blueprint for all proteins, these variants usually result in numerous differences ...

Diseases, Conditions, Syndromes

The genetic key to conquering cholera

Researchers have long understood that genetics can play a role in how susceptible people are to contracting cholera, but a team of Harvard scientists is now uncovering evidence of genetic changes that might also help protect ...

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