Establishing the way in which a genetic alteration called a TMPRSS2-ERG gene fusion forms in a prostate cancer, rather than the presence of the gene fusion itself, could help identify patients with prostate cancer with a ...
Nov 10, 2017
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A fusion gene occurs when a chromosomal break brings two separate genes together into a new functioning gene. So far, the research has focused on protein-coded fusion genes. However, human genes consist not only of protein-coded ...
Oct 5, 2017
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(HealthDay)—The fibroblast growth factor receptor 3 (FGFR3) transforming acidic coiled-coil containing protein 3 (TACC3) (FT3) gene fusion recruits endogenous TACC3 away from the mitotic spindle, resulting in errors in ...
Sep 18, 2017
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There are many ways a gene can be altered and there are many genes that, when altered, can cause cancer. Testing individually for each possible alteration in every cancer-related gene is not feasible as it would require hundreds ...
Aug 30, 2017
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A study by the University of Warwick sheds new light on gene fusion in bladder and brain cancer.
Aug 30, 2017
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An assay that identifies a peculiar but important abnormality in cancer cells has been developed and validated by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and ...
Aug 14, 2017
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Genetic mutations caused by rearranged chromosomes drive the development and growth of certain colorectal cancers, according to new research conducted by Weill Cornell Medicine investigators.
Jul 12, 2017
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Today, a team of investigators at Children's Hospital Los Angeles launched OncoKidsSM, a next-generation sequencing-based panel specifically designed for pediatric cancers. OncoKids is intended to guide the diagnosis and ...
Jun 21, 2017
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A detour on the road to regenerative medicine for people with muscular disorders is figuring out how to coax muscle stem cells to fuse together and form functioning skeletal muscle tissues. A study published June 1 by Nature ...
Jun 1, 2017
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A team of scientists has demonstrated the mechanism by which ETO2-GLIS2, a gene fusion, promotes the development of an aggressive form of pediatric leukemia. The findings, published in Cancer Cell, also reveal an opportunity ...
May 9, 2017
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