Alzheimer's disease & dementia

Study links inflammation to Alzheimer's disease development

Alzheimer's disease is a neurodegenerative condition that is characterized by the buildup of clumps of beta-amyloid protein in the brain. Exactly what causes these clumps, known as plaques, and what role they play in disease ...

Medical research

Protein shredder regulates fat metabolism in the brain

A protein shredder that occurs in cell membranes of brain cells apparently also indirectly regulates the fat metabolism. This is shown by a recent study by the University of Bonn. The shredder, known as gamma-secretase, is ...

Medical research

CRISPR helps identify potential Alzheimer's-related protein

Experts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "molecular scissors" of CRISPR/Cas9 to search for new genes related to the neurodegenerative ...

Alzheimer's disease & dementia

Novel compound is promising drug candidate for Alzheimer's disease

A newly identified compound is a promising candidate for inhibiting the production of amyloids, the abnormal proteins that form toxic clumps, called fibrils, inside the brains of patients with Alzheimer's disease. As published ...

Oncology & Cancer

Toward a safer treatment for leukemia

An international team of researchers at VIB-KU Leuven, Belgium, the U.K. Dementia Institute and the Children's Cancer Institute, Australia, have found a safer treatment for a specific type of leukemia. By refining a therapeutic ...

Alzheimer's disease & dementia

New player in Alzheimer's disease pathogenesis identified

Scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have shown that a protein called membralin is critical for keeping Alzheimer's disease pathology in check. The study, published in Nature Communications, ...

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