A small regulatory RNA called microRNA-155 appears to play a key role in the brain inflammation that helps foster Parkinson's disease. This finding, using a mouse model, implicates microRNA-155 as both a potential therapeutic ...
Feb 24, 2016
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Researchers led by a team at Baylor College of Medicine have identified a novel neurodevelopmental disorder associated with mutations or deletions affecting a gene called PAX5. Their findings are published in the journal ...
Jan 31, 2022
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Abolishing the 24-hour clock by knocking out a key gene during development accelerates aging and shortens lifespan by two thirds in mice, but this effect is absent if the gene deletion is delayed until after birth, according ...
Feb 3, 2016
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Researchers have defined the gene responsible for a rare developmental disorder in children. The team showed that rare variation in a gene involved in brain development causes the disorder. This is the first time that this ...
Nov 29, 2012
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A genetic study has identified neuronal abnormalities in the electrical activity of cortical cells derived from people with a rare genetic disorder called 22q11.2 deletion syndrome. The overexpression of a specific gene and ...
Sep 28, 2020
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Scientists have identified a gene which, when missing or impaired, can cause obesity, behavioral problems and, in mothers, postnatal depression. The discovery, reported in Cell, may have wider implications for the treatment ...
Jul 2, 2024
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This study suggests that genetically engineered malaria parasites that are stunted through precise gene deletions (genetically attenuated parasites, or "GAP") could be used as a vaccine that protects against malaria infection. ...
Sep 11, 2013
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A genetic screening approach to studying bone disease has found nine new genes associated with bone health and suggests a new way to discover genes that may be implicated in human skeletal diseases. A collaborative study ...
Aug 2, 2012
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Genes may now be deleted without creating a scar in certain strains of Escherichia coli and other microorganisms, thanks to A*STAR researchers. The technique makes it easier to string together several genetic engineering ...
Sep 25, 2015
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Researchers in France are taking advantage of the progress in genetic and molecular profiling to analyse the make-up of individual cancer patients' tumours and, using this information, assign them to particular treatments ...
Nov 8, 2012
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