Cell death is an essential physiological process for all multicellular organisms. Throughout life, cells in many tissues die naturally and are replaced by new cells. A proper balance between the death and production of new ...
Nov 8, 2016
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What makes healthy cells change and become dysfunctional to the point of causing disease? In addition to a disruption in genes that regulate cells, there is another factor in cell misbehavior that involves metabolism, say ...
Jun 24, 2019
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Scientists have discovered that the cells of early human embryos are often unable to repair damage to their DNA. The researchers say that this has important implications for the proposed use of gene editing techniques to ...
Jun 26, 2023
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Recombinant adeno-associated virus (rAAV) vectors for delivering therapeutic genes have demonstrated their safety in multiple diseases and clinical settings over the years and are a proven and effective tool that can be used ...
Mar 20, 2017
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A month ago, there were countless commentaries on the one-year anniversary of the news that Chinese researcher He Jiankui had created the world's first genome-edited twins.
Jan 6, 2020
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Scientists may now be able to predict whether carrying a specific genetic variant increases a person's risk for disease using gene editing and stem cell technologies, according to new research in the American Heart Association's ...
Jun 18, 2018
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Before the news broke internationally that Chinese scientist He Jiankui had allegedly genetically engineered twin girls, only a few people around the world had known about it. One of those was Penn cardiologist Kiran Musunuru.
Dec 12, 2019
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A Yale research team has designed a system to modify, or edit, multiple genes in the genome simultaneously, while also minimizing unintended effects. The gene-editing "toolbox" provides a user-friendly solution that scientists ...
Jul 26, 2016
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Mice don't get Alzheimer's—and while that's good news for mice, it's a big problem for biomedical researchers seeking to understand the disease and test new treatments. Now, researchers at The Jackson Laboratory are working ...
Jul 24, 2024
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Speaking today at the Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT) in Prague, Muhammad Mohiuddin, MBBS, said xenotransplantation, hailed as the future of organ ...
Apr 10, 2024
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