Oncology & Cancer

How alike are the cancer cells from a single patient?

Even within a single patient with cancer, there is a vast diversity of individual tumor cells, which display distinct behaviors related to growth, metastasis, and responses to chemotherapy. To carry out these behaviors, each ...

Genetics

Study links genes with function across the human brain

Many psychiatric disorders have genetic causes, but the exact mechanism of how genes influence higher brain function remains a mystery. A new study provides a map linking the genetic signature of functions across the human ...

Medical research

Molecular signatures can predict the efficacy of malaria vaccines

Molecular signatures before and after immunization can predict vaccine-induced protection, according to a study by ISGlobal. The study analysed the gene expression in peripheral blood cells from individuals immunized with ...

HIV & AIDS

New sequencing study provides insight into HIV vaccine protection

In a new study, scientists led by the U.S. Military HIV Research Program (MHRP) at the Walter Reed Army Institute of Research identified a transcriptional signature in B cells associated with protection from SIV or HIV infection ...

Medical research

Cellular engines of wound repair have distinct roles

Following tissue injury, fibroblast cells activate, divide and play key roles in both tissue repair and pathological scarring—fibrosis—that can drive organ failure.

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