We are more than the sum of our genes. Epigenetic mechanisms modulated by environmental cues such as diet, disease or lifestyle take a major role in regulating the DNA by switching genes on and off. It has been long debated ...
Jul 14, 2017
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Stem cell researchers at UCLA have generated the first genome-wide mapping of a DNA modification called 5-hydroxymethylcytosine (5hmC) in embryonic stem cells, and discovered that it is predominantly found in genes that are ...
Jul 21, 2011
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In 2009, the DNA alphabet expanded. Scientists discovered that an extra letter or "sixth nucleotide" was surprisingly abundant in DNA from stem cells and brain cells.
Oct 30, 2011
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The world of epigenetics—where molecular 'switches' attached to DNA turn genes on and off—has just got bigger with the discovery by a team of scientists from the University of Cambridge of a new type of epigenetic modification.
Dec 21, 2015
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An international collaborative research team, including scientists from UQ's Queensland Brain Institute (QBI), has discovered a novel mechanism underlying memory involving rapid changes in a specific DNA structure.
Apr 19, 2024
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With advances in genomics, scientists are discovering additional components of the DNA alphabet in animals. Do these unusual chemical modifications of DNA have a special meaning, or are they just signs that cellular machines ...
Oct 24, 2017
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Scientists from the German Center for Neurodegenerative Diseases have shed new light on the molecular basis of memory. Their study confirms that the formation of memories is accompanied by an altered activity of specific ...
Dec 18, 2015
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Scientists from the USC Stem Cell laboratory of Neil Segil have identified a natural barrier to the regeneration of the inner ear's sensory cells, which are lost in hearing and balance disorders. Overcoming this barrier may ...
Jul 30, 2021
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A recent study has reported that changes in mice sperm microRNAs brought about by aging may affect the growth and development of offspring. The finding adds to the growing literature on the effects of paternal aging on offspring.
Jan 12, 2024
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You might think that the DNA you inherited is one thing that you absolutely can't do anything about, but in one sense you'd be wrong. Researchers reporting in the March issue of Cell Metabolism, a Cell Press publication, ...
Mar 6, 2012
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