Neuroblastoma, a rare childhood cancer of the sympathetic nervous system, is particularly deadly because it is difficult to detect and thus generally advanced before treatment begins. Scientists know that neuroblastoma develops ...
Jul 6, 2018
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Two women have the same genetic mutation – an abnormal BRCA1 gene that puts them both at much higher-than-average risk for breast cancer – but only one woman develops the disease. Why? Michigan State University genetic ...
Aug 1, 2013
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How do you build a brain? What "rules" govern where neurons end up, how they connect to each other, and which functions they perform?
Dec 10, 2018
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Researchers have reverse-engineered the outlines of a disrupted prenatal gene network in schizophrenia, by tracing spontaneous mutations to where and when they likely cause damage in the brain. Some people with the brain ...
Aug 1, 2013
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By combining whole exome sequencing, machine learning, and network analysis, researchers have identified new, ultra-rare gene mutations within specific biological pathways that may contribute to eating disorders.
Sep 5, 2017
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When it comes to training neural circuits for tissue engineering or biomedical applications, a new study suggests a key parameter: Train them young.
Aug 6, 2020
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Scientists investigating heart failure have been limited to studying diseased heart tissue in the lab—understandably, as people don't tend to pluck out a healthy heart for the sake of research. But now, scientists with ...
Jun 24, 2019
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(Medical Xpress)—Researchers in China have developed a technique for reprogramming cells found in urine into neural progenitor cells that are capable of growing into neurons. In their paper published in Nature Methods, ...
Prescriptions for multiple drugs, or polypharmacy, is often recommended for the treatment of complex diseases. However, upon ingestion, multiple drugs may interact in an undesirable manner, resulting in severe adverse effects ...
May 4, 2022
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Wilmot Cancer Institute researchers are a step closer to understanding the complex gene interactions that cause a cell to become malignant. In a new Cell Reports study published today, the group used network modeling to hone ...
Dec 21, 2021
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