Diabetes

New diabetes risk mechanism identified

Researchers at Mayo Clinic have discovered an unexpected effect from a gene known to increase diabetes risk. They assumed that the specific allele in the gene TCF7L2 which increases the risk of type 2 diabetes, impairs insulin ...

Medical research

Loss of a gene can be compensated by another gene

New methods for modifying the genome are currently widely discussed: Using CRISPR/Cas for instance, scientists can remove parts of the genetic code of a gene, thereby knocking it out. Furthermore, there are ways to inhibit ...

Genetics

Focusing in on high-resolution network biology

A central challenge in genetics is to understand how changes in DNA result in observable changes in an organism; how genotype maps to phenotype. As genes and their protein products do not act in isolation, connecting genotype ...

Diseases, Conditions, Syndromes

Drug may guard against periodontitis, and related chronic diseases

A drug currently used to treat intestinal worms could protect people from periodontitis, an advanced gum disease, which untreated can erode the structures—including bone—that hold the teeth in the jaw. The research was ...

Diseases, Conditions, Syndromes

Better insights into treating hepatitis C

With nearly 200 million infected people worldwide, hepatitis C virus (HCV) represents a significant public health issue. One of the most important challenges is that although the immune system seems to be responsible for ...

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