A recently developed system for switching on the activity of genes could improve treatments for a broad range of neurological diseases. Esteban Engel, a researcher in viral neuroengineering in the Princeton Neuroscience Institute, ...
Apr 17, 2020
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Over the last decade, it has made good sense to study the genetic drivers of cancer by sequencing a tiny portion of the human genome called the exome - the 2% of our three billion base pairs that "spell out" the 21,000 genes ...
May 8, 2017
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Data in a study published in the Archives of General Psychiatry suggest that certain variants of a gene that helps regulate serotonin (a brain chemical related to mood), may serve as a useful predictor of risk for symptoms ...
Sep 5, 2011
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Sophisticated genetic tools and techniques for achieving targeted gene delivery and high gene expression levels in bone marrow will drive the successful application of gene therapy to treat a broad range of diseases. Examples ...
Jun 27, 2011
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A mutation that helps make cells immortal is critical to the development of a tumor, but new research at the University of California, Berkeley suggests that becoming immortal is a more complicated process than originally ...
Aug 17, 2017
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Around 98.5% of human DNA is non-coding, meaning it doesn't get copied to make proteins. A new study has connected many of these non-coding regions to the genes they affect and laid out guidelines for how researchers can ...
Mar 19, 2024
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New research proves that a change in a particular gene can identify which patients with a specific kind of brain cancer will respond better to treatment. Testing for the gene can distinguish patients with a more- or less-aggressive ...
May 31, 2011
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Mariusz A. Wasik, MD, professor of Pathology and Laboratory Medicine, and Qian Zhang, MD, PhD, research assistant professor, both from the Perelman School of Medicine at the University of Pennsylvania, and their colleagues, ...
Aug 10, 2011
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A genome-wide survey by researchers at The Wistar Institute shows how our cells create alternate versions of mRNA transcripts by altering how they "read" DNA. Many genes are associated with multiple gene promoters, the researchers ...
Jul 11, 2011
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Like a Russian bot corrupting U.S. elections, or a new prime minister wreaking havoc in the U.K., a protein named BORIS is showing itself to be a malevolent player in some childhood cancers. New research fingers BORIS as ...
Sep 25, 2019
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