A team led by researchers at UT Southwestern Medical Center has developed deep learning models to identify a simple set of rules that govern the activity of promoters—regions of DNA that initiate the process by which genes ...
May 14, 2024
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Around 98.5% of human DNA is non-coding, meaning it doesn't get copied to make proteins. A new study has connected many of these non-coding regions to the genes they affect and laid out guidelines for how researchers can ...
Mar 19, 2024
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A new editorial paper has been published in Oncoscience, titled, "Be mindful of potential pitfalls when using the Cre-LoxP system in cancer research."
Dec 4, 2023
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TNBC is a particularly aggressive subtype of breast cancer, characterized by the absence of three key receptors: estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). Approximately ...
Jul 25, 2023
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A new research paper was published in Genes & Cancer on December 14, 2022, entitled, "Slit2 signaling stimulates Ewing sarcoma growth."
Jan 16, 2023
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A recently developed system for switching on the activity of genes could improve treatments for a broad range of neurological diseases. Esteban Engel, a researcher in viral neuroengineering in the Princeton Neuroscience Institute, ...
Apr 17, 2020
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Like a Russian bot corrupting U.S. elections, or a new prime minister wreaking havoc in the U.K., a protein named BORIS is showing itself to be a malevolent player in some childhood cancers. New research fingers BORIS as ...
Sep 25, 2019
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Australian and US researchers have developed a way to discover elusive cancer-promoting genes, and have already identified one that appears to promote aggressive breast cancers.
Mar 8, 2019
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Gastric cancer cells are helped to evade the immune system by alterations in gene regulation, according to new work by A*STAR researchers. This mechanism might apply to a wide range of cancers, and could be exploited to improve ...
Oct 19, 2017
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A mutation that helps make cells immortal is critical to the development of a tumor, but new research at the University of California, Berkeley suggests that becoming immortal is a more complicated process than originally ...
Aug 17, 2017
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