Genetics

New research maps possible molecular origins of kidney disease

After mapping the genetic underpinning of kidney function in 1.5 million people and about 60,000 kidney cells that are the microscopic mechanisms of gene regulation, researchers at the Perelman School of Medicine at the University ...

Diseases, Conditions, Syndromes

Herpes cure with gene editing makes progress in laboratory studies

Researchers at Fred Hutch Cancer Center have found in pre-clinical studies that an experimental gene therapy for genital and oral herpes removed 90% or more of the infection and suppressed how much virus can be released from ...

Genetics

Progress in refining the genetic causes of schizophrenia

The study, published today in Genome Biology and funded by the Medical Research Council, combined genetic sequence information with measures of gene regulation in schizophrenia patients and matched controls.

Oncology & Cancer

Cancer cells' plasticity makes them harder to stop

When metastatic cancer cells need to avoid a threat, they simply reprogram themselves. Rice University scientists are beginning to get a handle on how they survive hostile environments.

Genetics

Role of gene regulator in skeletal muscles demonstrated

Fast muscles, such as the thigh muscle in a sprinter, deliver energy quickly but fatigue quickly. Slow muscles, such as the soleus muscle in the lower calf, are less forceful but important for posture and endurance. Researchers ...

Genetics

3D map reveals DNA organization within human retina cells

National Eye Institute researchers mapped the organization of human retinal cell chromatin, the fibers that package 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each cell's ...

Genetics

New method created for identifying genes behind brain tumors

Researchers at Uppsala University have developed a method for identifying functional mutations and their effect on genes relevant to the development of glioblastoma—a malignant brain tumor with a very poor prognosis. The ...

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