Mutating cells can prevent the spread of cancer by flipping themselves into a state of reduced activity called senescence. Cancer genes, however, can retaliate by reviving those cells so they can replicate again.
Apr 21, 2023
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Researchers at Cleveland Clinic have taken an important step in predicting which treatment will work for individual cancer patients. Using a gene signature developed from cell lines and human tissue, the research team demonstrated ...
Apr 20, 2023
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A Matrix Biology paper by the Werner group (IMHS) shows how wound healing gene expression signatures are expressed in tumors and can be used to predict cancer outcome. The paper establishes a functional link between wound ...
Mar 27, 2023
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In a paper published in PNAS, Maureen Murphy, Ph.D., Deputy Director of Wistar's Ellen and Ronald Caplan Cancer Center and Ira Brind Professor and Program Leader in the Molecular & Cellular Oncogenesis Program, and team have ...
Feb 6, 2023
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Among premenopausal women with hormone receptor (HR)-positive, early-stage breast cancer enrolled in the SOFT trial, those with a high score on a genomic assay called Breast Cancer Index (BCI) had increased risk of distant ...
Dec 6, 2022
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Researchers from the University of Missouri School of Medicine have discovered how obstructive sleep apnea (OSA) changes the profiles of immune cells in the blood, leading to a unique cellular signature that can accurately ...
Nov 15, 2022
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The mitochondria is a key energy-producing component of the human cell that plays an important role in cancer cell metabolism. In a research paper published in PLOS ONE, Dario C. Altieri, M.D., president and chief executive ...
Oct 12, 2022
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Researchers at the Francis Crick Institute have developed a method that could help predict whether people with lung cancer will respond to chemotherapy, based on which genes are switched on in their tumor.
Oct 3, 2022
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Two years ago, University of Alabama at Birmingham researchers and colleagues reported that reductive stress—an imbalance in the normal oxidation/reduction, or redox, homeostasis—caused pathological changes associated ...
Aug 3, 2022
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Investigators from Cedars-Sinai Cancer have identified genetic signatures that could predict whether tumors in patients with bladder and other cancers will respond to immunotherapy. Their results, published today in the Journal ...
Aug 3, 2022
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