Medical research

Gene expression mechanism may have immunity, cancer implications

Alternative polyadenylation (APA) is an RNA processing mechanism that regulates gene expression by generating different ends on RNA transcripts of the same gene. Though it affects more than half of human genes, the significance ...

Oncology & Cancer

New computational models to understand colon cancer

Although the development of secondary cancerous growths, called metastasis, is the primary cause of death in most cancers, the cellular changes that drive it are poorly understood. In a new study, published in Genome Biology, ...

Oncology & Cancer

Gene network for leukemia factor

Transcription factors—proteins that regulate gene expression—play critical roles in cell fate decisions and are frequent targets of mutation in a variety of human cancers. Understanding how transcription factors contribute ...

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