Genetics

Scientists map genes controlling immune system 'brakes'

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed. Now, researchers ...

Medical research

A master regulator of kidney health?

End-stage kidney disease often begins with injury to podocytes. These highly specialized cells are a critical part of the glomeruli, clusters of capillaries that serve as the filtration units in our kidneys' tightly-packed ...

Oncology & Cancer

Gene-controlling mechanisms play key role in cancer progression

As cancer cells evolve, many of their genes become overactive while others are turned down. These genetic changes can help tumors grow out of control and become more aggressive, adapt to changing conditions, and eventually ...

Oncology & Cancer

New treatment target verification for myelodysplastic syndrome

A research group from Kumamoto University, Japan, analyzed the pathophysiology of myelodysplastic syndrome (MDS), a blood cancer that presents often in the elderly, and found the presence of the transcription factor RUNX3, ...

Oncology & Cancer

Pregnancy reprograms breast cells, reducing cancer risk

An early age of pregnancy (25 years and younger) is known to reduce the overall risk of breast cancer by over 30%. CSHL Assistant Professor Camila dos Santos spent several years teasing out the molecular details behind the ...

Neuroscience

Adult astrocytes are key to learning and memory

Researchers at Baylor College of Medicine reveal that astrocytes, the most abundant cells in the brain, play a direct role in the regulation of neuronal circuits involved in learning and memory. The findings appear in the ...

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