Many genes linked to late-onset Alzheimer's disease (AD) are expressed in myeloid cells and regulated by a single protein, according to research conducted at the Icahn School of Medicine at Mount Sinai and published June ...
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The immune system is a formidable defense against microbial intruders, identifying and eliminating threats through an extremely intricate and adaptable network of specialized cells. However, a system of such deep complexity ...
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Stop-and-go traffic is typically a source of frustration, an unneccesary hold-up on the path from point A to point B. But when it comes to the molecular machinery that copies our DNA into RNA, a stop right at the beginning ...
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Michigan State University researchers have discovered that a chemical compound, and potential new drug, reduces the spread of melanoma cells by up to 90 percent.
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In a bid to better understand the gene expression patterns that control T cell activity, researchers at the La Jolla Institute for Allergy and Immunology mapped genome-wide changes in chromatin accessibility as T cells respond ...
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Genetics play a strong part in the development of attention-deficit/hyperactivity disorder (ADHD), but the path from a gene to risk for the disorder has remained a black box to researchers.. A new study in Biological Psychiatry ...
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Scientists at Johns Hopkins say they are one step closer to understanding the genetic mechanism of a rare, complex, multiple-gene disorder called Hirschsprung's disease. The results of their latest study suggest that many ...
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A study from Oxford and Basel universities may point the way to maintaining our immune systems as we get older.
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Results of preclinical studies by MUSC investigators reported in the July 2016 issue of PLOS One, demonstrate for the first time that the transcription factor KLF12 promotes CRC cell growth, in part, by activating EGR1. Furthermore, ...
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People with Rett Syndrome, a rare and debilitating neurodevelopmental disorder, exhibit many autism-like traits. Now researchers at MIT have identified a protein that plays an important role in the disorder. The researchers ...
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