Alzheimer's disease & dementia

Experimental Alzheimer's drug improves memory in mice

An experimental drug known as A03, which was previously developed to treat depression, increases the levels of the enzyme Sirtuin1, or SirT1, and improves memory in mice. The mice were genetically modified to have a protein ...

Genetics

First common risk genes discovered for autism

A study headed by researchers from the Danish project iPSYCH and the Broad Institute in the U.S., has found the first common genetic risk variants for autism and uncovered genetic differences in clinical subgroups of autism. ...

Immunology

Extinct human species gave modern humans an immunity boost

Findings from the Garvan Institute of Medical Research show modern humans acquired a gene variant from Denisovans that heightened their immune reactions, indicating adaptation of the immune system to a changing environment.

Medical research

X chromosomes linked to male infertility identified

An international team of researchers has identified multiple X chromosomes that likely contribute to infertility in men. In their paper published in The American Journal of Human Genetics, the researchers describe how they ...

Genetics

New hope for blinding eye disease gene therapies

New opportunities towards gene therapy and diagnosis for the blinding eye disease, retinal dystrophy, may now become available following work done by the Eye Genetics Research Unit at Children's Medical Research Institute.

Diabetes

Melatonin signaling is a risk factor for type 2 diabetes

A sleeping pancreas releases less insulin, but how much insulin drops each night may differ from person to person, suggests a study published May 12, 2016 in Cell Metabolism. Up to 30 percent of the population may be predisposed ...

Attention deficit disorders

New gene study of ADHD points to defects in brain signaling pathways

Pediatric researchers analyzing genetic influences in attention-deficit/hyperactivity disorder (ADHD) have found alterations in specific genes involved in important brain signaling pathways. The study raises the possibility ...

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