Oncology & Cancer

Synonymous genetic alterations: Not 'silent' at all

The so-called "silent" or "synonymous" genetic alterations do not result in altered proteins. But they can nevertheless influence numerous functions of the cell and thus also disease processes. Scientists from the German ...

Oncology & Cancer

FDA approves personalized therapy for metastatic bladder cancer

(HealthDay)—The first personalized treatment for patients with metastatic bladder cancer and susceptible fibroblast growth factor receptor (FGFR) genetic alterations was granted accelerated approval by the U.S. Food and ...

Medical research

DF-PGT, now possible through massive sequencing techniques

A research team from the Universitat Autònoma de Barcelona (UAB), in collaboration with the Blood and Tissue Bank of Catalonia, has implemented a massive sequencing platform for preimplantation genetic testing (PGT) for ...

Oncology & Cancer

Fishing for new leads in a rare melanoma

Zebrafish are an emerging power tool in cancer research. They can be engineered to light up when certain genes turn on—capturing the moment when a cancer is initiated. Because they breed so quickly, they lend themselves ...

Oncology & Cancer

A novel data-driven method to personalize cancer treatment

Identifying and prioritizing treatment options based on a patient's profile of genetic alterations is a major challenge in personalized cancer medicine. A new data-driven approach called PanDrugs can help to this end. This ...

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