Genetics

New genome-editing strategy could lead to therapeutics

Researchers at UMass Medical School have developed a genome-editing strategy to correct disease-causing DNA mutations in mouse models of human genetic diseases, according to research published in the Aug. 18 edition of Nature ...

Genetics

Genetic diversity impacts disease severity

New research offers clues as to why some diseases are highly variable between individuals. The phenomenon is apparent in people with retinitis pigmentosa, a condition that causes the light-sensing cells in the eye to degenerate. ...

Genetics

Variants in non-coding DNA contribute to inherited autism risk

In recent years, researchers have firmly established that gene mutations appearing for the first time, called de novo mutations, contribute to approximately one-third of cases of autism spectrum disorder (ASD). In a new study, ...

Diseases, Conditions, Syndromes

Typhoid outbreak—genetic cause of extensive drug resistance found

The genetic cause behind a strain of typhoid's resistance to five classes of antibiotics has been uncovered by scientists at the Wellcome Sanger Institute and their collaborators at Public Health England and Aga Khan University, ...

Autism spectrum disorders

Genetic targets for autism spectrum disorder identified

Autism is a spectrum of closely related symptoms involving behavioral, social and cognitive deficits. Early detection of autism in children is key to producing the best outcomes; however, searching for the genetic causes ...

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