Genetics

New survey of DNA alterations could aid search for cancer genes

Scanning the DNA of nearly 5,000 tumor samples, a team led by scientists at Dana-Farber Cancer Institute and the Broad Institute has identified 140 regions of scrambled genetic code believed to contain many undiscovered cancer ...

Neuroscience

Memory-related brain network shrinks with aging

Brain regions associated with memory shrink as adults age, and this size decrease is more pronounced in those who go on to develop neurodegenerative disease, reports a new study published Sept. 18 in the Journal of Neuroscience ...

Oncology & Cancer

Major cancer genotyping study logs 5,000th tumor profile

More than 5,000 genetic profiles of tumor DNA have been completed in a large research study by scientists at Dana-Farber Cancer Institute, Brigham and Women's Hospital, and Boston Children's Hospital designed to speed the ...

Oncology & Cancer

Genetic make-up of rare gastrointestinal tract tumour decoded

Gastrointestinal stromal tumours (GIST) are relatively rare tumours of the gastrointestinal tract that can occur both as a harmless incidental finding and as aggressive, malignant disease. Two key genetic mutations that can ...

Parkinson's & Movement disorders

Early-onset Parkinson's disease linked to genetic deletion

Toronto, Canada – Scientists at the Centre for Addiction and Mental Health (CAMH) and University Health Network (UHN) have found a new link between early-onset Parkinson's disease and a piece of DNA missing from chromosome ...

Genetics

Moving towards gene therapies for retinal atrophies

Researchers at Michigan State University (MSU) provide the first phenotypic evidence a mutated gene causes one form of progressive retinal atrophy in papillon dogs. Progressive retinal atrophy is analogous to one of the leading ...

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