Northwestern Medicine scientists have discovered new insights into the production and regulation of a class of noncoding RNAs and how alterations in their signatures diversify and modulate the transcriptome of three major ...
Aug 5, 2024
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As part of a breast cancer diagnosis, pathologists take cells from a biopsy and check them under a microscope. Most cancerous cells form roundish clumps, known as no special type, or invasive ductal carcinoma (IDC). In fewer ...
Jul 24, 2024
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Most research in human genetics has historically focused on people of European ancestries—a long-standing bias that may limit the accuracy of scientific predictions for people from other populations.
Jul 17, 2024
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Understanding the molecular characteristics of cancer that impact patient outcomes is essential to identifying novel treatment strategies for the most intractable pediatric malignancies. Many of these diseases are difficult ...
Jun 26, 2024
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An unsuspected gene, Glis2, has been found to be a target of polycystic kidney disease (PKD) signaling in preclinical models.
Jun 13, 2024
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In disease research, it's important to know gene expression and where in a tissue the expression is happening, but marrying the two sets of information can be challenging.
Jun 4, 2024
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Epigenetics, a term coined by Conrad H. Waddington in the early 1940s, originally described the complex molecular pathways that govern how a genotype manifests as a phenotype. Over time, this definition has evolved to focus ...
May 31, 2024
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A comprehensive approach that examines the intersection of multiple biological processes is necessary to elucidate the development of stress-related disorders. In a new study, investigators from McLean Hospital, a member ...
May 23, 2024
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A new analysis has revealed detailed information about genetic variation in brain cells that could open new avenues for the targeted treatment of diseases such as schizophrenia and Alzheimer's disease.
May 23, 2024
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A new advanced artificial intelligence (AI) algorithm may lead to better—and earlier—predictions and novel therapies for autoimmune diseases, which involve the immune system mistakenly attacking their body's own healthy ...
May 20, 2024
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