Genetics

New research shows childhood adversity causes changes in genetics

In a look at how major stressors during childhood can change a person's biological risk for psychiatric disorders, researchers at Butler Hospital have discovered a genetic alteration at the root of the association. The research, ...

Diabetes

Genetic study links body clock receptor to diabetes

A study published in Nature Genetics today has found new evidence for a link between the body clock hormone melatonin and type 2 diabetes. The study found that people who carry rare genetic mutations in the receptor for melatonin ...

Medical research

Worms reveal secrets of wound-healing response

The lowly and simple roundworm may be the ideal laboratory model to learn more about the complex processes involved in repairing wounds and could eventually allow scientists to improve the body's response to healing skin ...

Genetics

Large meta-analysis finds new genes for type 1 diabetes

The largest-ever analysis of genetic data related to type 1 diabetes has uncovered new genes associated with the common metabolic disease, which affects 200 million people worldwide. The findings add to knowledge of gene ...

Genetics

New biochemical discoveries into developing disease

Researchers have undertaken the most comprehensive investigation of genetic variance in human metabolism and discovered new insights into a range of common diseases. Their work has revealed 37 new variants that are associated ...

Genetics

Stem cell model offers clues to cause of inherited ALS

An international team of scientists led by researchers at the University of California, San Diego School of Medicine have used induced pluripotent stem cells (iPSCs) derived from patients with amyotrophic lateral sclerosis ...

Medical research

Researchers link cell division and oxygen levels

Cells grow abundant when oxygen is available, and generally stop when it is scarce. Although this seems straightforward, no direct link ever has been established between the cellular machinery that senses oxygen and that ...

Genetics

Researchers discover 'master switch' gene for obesity, diabetes

A team of researchers, led by King's College London and the University of Oxford, have found that a gene linked to type 2 diabetes and cholesterol levels is in fact a 'master regulator' gene, which controls the behaviour ...

Inflammatory disorders

Rare metabolic disorder can cause liver inflammation

Millions of people worldwide suffer from liver inflammation (hepatitis), an acute or chronic disease with a variety of causes. Liver inflammation frequently occurs in connection with metabolic disorders, for example fatty ...

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