Most cancer drugs that target specific genetic mutations are designed for adult cancers rather than those in children, partly because pediatric cancers have fewer mutations. To look for more ways to target childhood cancers, ...
Mar 23, 2021
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The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease.
Dec 21, 2020
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Researchers from the newly-established Center for Neural Circuit Mapping at the University of California, Irvine School of Medicine evaluate the properties of anterograde and retrograde viral tracers, comparing their strengths ...
Aug 4, 2020
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A comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 genetic screens in 725 cancer models, across 25 different cancer types. Scientists at ...
Dec 20, 2019
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Environmental enrichment can partially correct miswired neurons in the visual pathway, according to research in mice recently published in eNeuro.
Nov 25, 2019
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The genetic mechanism of hereditary human hair diseases, such as alopecia and thinning hair, has drawn much attention in human genetics research, yet many questions around this mechanism persist. A recent animal study in ...
Nov 21, 2019
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The nonstructural protein 1 (NS1) of the dengue virus interacts with another viral protein called NS4A-2K-4B to enable viral replication, according to a study published May 9 in the open-access journal PLOS Pathogens by Ralf ...
May 9, 2019
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Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in the process becoming dependent on those genes for their survival and growth. The resulting ...
Apr 11, 2019
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Take two cancer cells and compare their genomes. Surprisingly, they can be quite different. This genetic variation is one of the hallmarks of cancer, and one reason why treating cancer is so hard.
Feb 21, 2019
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Researchers have developed a 3-D map of the gene interactions that play a key role in cardiovascular disease, a study in eLife reports.
Jul 10, 2018
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