Columbia researchers have restored normal working memory to a mouse model of schizophrenia, eliminating a core symptom of the disorder that, in people, has proven virtually impossible to treat.
Oct 9, 2019
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Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered that one of the most common genetic alterations in autism -- deletion of a 27-gene cluster on chromosome 16 -- causes autism-like features. By generating ...
Oct 3, 2011
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Researchers have identified a new protein involved in the development of drug resistance in breast cancer which could be a target for new treatments, they report today in the journal Nature Medicine.
May 22, 2011
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MIT cancer biologists have identified a genetic change that makes lung tumors more likely to spread to other parts of the body. The findings, to be published in the April 6 online issue of Nature, offers new insight into ...
Apr 6, 2011
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A genetic disorder leads to an increase in bioactive lipids in the brain, resulting in an imbalance between excitation and inhibition in neural circuits and promoting mental disorders. However, treatment with an enzyme inhibitor ...
Jun 6, 2024
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As humans age, hematopoietic stem cells—the immature precursor cells that give rise to all blood and immune cells—accumulate mutations. Some of the mutations allow these stem cells to self-renew and expand more effectively ...
Jun 5, 2024
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A research group led by University of Tsukuba has discovered a mouse pedigree that presents spontaneous sudden cardiac death attributed to inherited ventricular arrhythmia. This was identified through electrocardiographic ...
May 15, 2024
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By completely or even partially depleting a protein called midnolin in B cells, UT Southwestern Medical Center researchers suppressed leukemia and lymphoma in a mouse model genetically prone to these cancers.
May 15, 2024
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Some infants are born with too few nephrons, the filtering units in kidneys that help the body remove waste and excess fluid. Whether due to low birth weight, maternal diabetes, inadequate nutrition or genetic mutations, ...
Mar 15, 2024
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University of Adelaide researchers now know more about a mysterious gene's role in maintaining healthy DNA—a crucial development that could lead to new treatments for life-threatening illnesses including neurodevelopmental ...
Mar 13, 2024
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