Genetics

Researchers discover treatment option for rare genetic disorder

Researchers from the Icahn School of Medicine used a novel genetic sequencing technology to identify the genetic cause of—and a treatment for—a previously unknown severe auto inflammatory syndrome affecting an 18-year-old ...

Genetics

Surprisingly many peculiar long introns found in brain genes

In a recent study of genes involved in brain functioning, their previously unknown features have been uncovered by bioinformaticians from the Moscow Institute of Physics and Technology and the Institute of Mathematical Problems ...

Genetics

New genomic atlas of the developing human brain

For the nascent brain of a human embryo to develop into the complex organ that controls human consciousness, a finely tuned sequence of genetic events has to take place; hundreds of genes are activated and deactivated in ...

Diseases, Conditions, Syndromes

UN: China's latest virus outbreak likely came from Europe

The emergencies chief of the World Health Organization confirmed Friday that the U.N. agency received genetic sequences from China involving Beijing's recent coronavirus outbreak and said it appears the virus was exported ...

page 1 from 46

DNA sequence

A DNA sequence or genetic sequence is a succession of letters representing the primary structure of a real or hypothetical DNA molecule or strand, with the capacity to carry information as described by the central dogma of molecular biology.

The possible letters are A, C, G, and T, representing the four nucleotide bases of a DNA strand — adenine, cytosine, guanine, thymine — covalently linked to a phosphodiester backbone. In the typical case, the sequences are printed abutting one another without gaps, as in the sequence AAAGTCTGAC, read left to right in the 5' to 3' direction. Short sequences of nucleotides are referred to as oligonucleotides and are used in a range of laboratory applications in molecular biology. With regard to biological function, a DNA sequence may be considered sense or antisense, and either coding or noncoding. DNA sequences can also contain "junk DNA."

Sequences can be derived from the biological raw material through a process called DNA sequencing.

In some special cases, letters besides A, T, C, and G are present in a sequence. These letters represent ambiguity. Of all the molecules sampled, there is more than one kind of nucleotide at that position. The rules of the International Union of Pure and Applied Chemistry (IUPAC) are as follows:

This text uses material from Wikipedia, licensed under CC BY-SA