Medical research
Targeting bicarbonate in cancer
Bicarbonate ions are required for cell growth in some cancers, according to a Northwestern Medicine study published in the journal Molecular Cell.
Jul 12, 2022
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News tagged with genetic therapy
Genetics
Cell therapy for lung disease? Proof-of-concept study shows promise
Many serious pulmonary diseases, including genetic lung diseases, lack an effective treatment other than the most extreme: lung transplant. A team at Boston Children's Hospital envisions a much better option: cell therapy, ...
Jun 23, 2022
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Genetics
Hope for treatments against hearing loss as 10 genes identified
Researchers led by King's College London, Karolinska Institute and Erasmus University have identified 10 new genes linked with hearing loss and located the part of the ear affected.
May 16, 2022
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Oncology & Cancer
Research team discovers new target for CAR T cells in solid tumors
Chimeric antigen receptor T-cell therapy, or CAR T, has made a big impact on the treatment of certain blood cancers, allowing patients with relapsed/refractory disease to live longer, healthier lives. But in clinical study, ...
May 5, 2022
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Medical research
Research supports development of new suppressor-tRNA-based gene therapies
Gene therapy researchers at UMass Chan Medical School have shown the first evidence that a suppressor transfer RNA (tRNA) therapy can restore protein production up to six months after treatment in a mouse model of the rare ...
Apr 21, 2022
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Oncology & Cancer
Methionine restriction may improve aggressive brain cancer prognosis in children
Some brain cancers are easier to treat than others. Many solid tumors can be carefully excised by a skilled neurosurgeon, but others, such as diffuse midline gliomas, or DMGs, are much trickier. Children who have been diagnosed ...
Apr 14, 2022
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Health
Insomnia could increase people's risk of type 2 diabetes, study finds
People who have difficulty getting to sleep or staying asleep had higher blood sugar levels than people who rarely had sleep issues, new research has found. The findings suggest insomnia could increase people's risk of type ...
Apr 7, 2022
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Neuroscience
Replacing microglia in mice using circulation-derived myeloid cells to treat neurodegenerative disease
An international team of researchers has developed a way to replace almost all of the microglia cells in a mouse brain using circulation-derived myeloid cells as a way to treat neurodegenerative disease using a technique ...
Diseases, Conditions, Syndromes
Muscle stem cell technology a prelude to new muscular dystrophy therapeutics
Scientists at UMass Chan Medical School have developed a technology to isolate human skeletal muscle stem cells, or progenitor cells, from induced pluripotent stem cells (iPSCs). Christened iMyoblasts in an eLife paper by ...
Mar 17, 2022
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Medical research
Discovery of a new ALS and dementia disease mechanism raises treatment hopes
A pioneering new study led by UCL and National Institutes of Health (NIH) scientists has revealed, for the first time, why a common genetic variant worsens disease outcomes for people with the devastating adult-onset neurodegenerative ...
Feb 23, 2022
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