Genetics

Artificial RNA editing with ADAR for gene therapy

Many of the diseases caused by point mutations have no established therapeutic approaches. Prof. Tsukahara and colleagues (Japan Advanced Institute of Science and Technology) are studying a therapeutic method using artificial ...

Genetics

Perspectives on gene editing

Medicine is at a turning point, on the cusp of major change as disruptive technologies such as gene, RNA, and cell therapies enable scientists to approach diseases in new ways. The swiftness of this change is being driven ...

Genetics

Why we are not ready for genetically designed babies

The media is buzzing with the surprise news that a Chinese researcher, Jainkui He, has created the world's first genome-edited twins. He did this, ostensibly, to provide resistance to HIV, the virus that causes AIDS.

Genetics

New genome-editing strategy could lead to therapeutics

Researchers at UMass Medical School have developed a genome-editing strategy to correct disease-causing DNA mutations in mouse models of human genetic diseases, according to research published in the Aug. 18 edition of Nature ...

Genetics

Heritable genome editing could become 'morally permissible'

An independent inquiry led by Nuffield Council on Bioethics, involving UCL, has concluded that editing the DNA of a human embryo, sperm, or egg to influence the characteristics of a future person ('heritable genome editing') ...

HIV & AIDS

Genome editing method targets AIDS virus

By destroying the regulatory genes of the AIDS virus HIV-1 using the genome editing system CRISPR/Cas9, a Japanese research group has succeeded in blocking the production of HIV-1 by infected cells.

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