Genetics

New strategy IDs infertility-causing genes

Infertility affects roughly 15 percent of couples – with many cases resulting from faulty genetics – but the details of underlying genetic causes are largely unknown.

Immunology

In CRISPR advance, scientists successfully edit human T cells

In a project spearheaded by investigators at UC San Francisco, scientists have devised a new strategy to precisely modify human T cells using the genome-editing system known as CRISPR/Cas9. Because these immune-system cells ...

Genetics

A novel technique for gene insertion by genome editing

Using a novel gene knock-in technique, effective insertion of an exogenous gene was demonstrated in human cells and in animal models, including silkworms and frogs. This strategy universally enables gene knock-in not only ...

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