UNSW Australia researchers have shown that changing just a single letter of the DNA of human red blood cells in the laboratory increases their production of oxygen-carrying haemoglobin - a world-first advance that could lead ...
May 14, 2015
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Researchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) have used CRISPR/Cas9 technology to engineer donor T cells to try to treat seriously ill ...
Oct 27, 2022
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A novel gene editing technique developed by researchers at The Ohio State University Wexner Medical Center and College of Medicine is showing promise in correcting genetic mutations in Duchenne muscular dystrophy (DMD) and ...
Jun 25, 2021
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The media is buzzing with the surprise news that a Chinese researcher, Jainkui He, has created the world's first genome-edited twins. He did this, ostensibly, to provide resistance to HIV, the virus that causes AIDS.
Nov 28, 2018
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A major challenge in human genetics is understanding which parts of the genome drive specific traits or contribute to disease risk. This challenge is even greater for genetic variants found in the 98% of the genome that does ...
May 4, 2023
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Revealing surprising answers to a long-standing enigma about the brain target of the anti-obesity hormone leptin, neuroscientists at Tufts University School of Medicine have used CRISPR genome editing to identify a neural ...
Apr 18, 2018
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Using a novel gene knock-in technique, effective insertion of an exogenous gene was demonstrated in human cells and in animal models, including silkworms and frogs. This strategy universally enables gene knock-in not only ...
Dec 2, 2014
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Scientists rely on the use of animal models to improve our understanding of lethal muscle-wasting disease Duchenne muscular dystrophy (DMD), and to develop safe new therapies. A newly developed rabbit model, created through ...
Jun 4, 2018
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An independent inquiry led by Nuffield Council on Bioethics, involving UCL, has concluded that editing the DNA of a human embryo, sperm, or egg to influence the characteristics of a future person ('heritable genome editing') ...
Jul 24, 2018
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This winter has provided several dramatic developments in the ongoing debate about whether altering the "germline" - that is, the genome of a new embryo - should be allowed. Employing the technique could permanently alter ...
Feb 25, 2016
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