Researchers at the University of Helsinki, Finland, have uncovered a mechanism through which a mutation in the STAT3 gene leads to a disorder in the development of the pancreas and to infant diabetes.
Apr 11, 2017
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When the National Academy of Sciences (NAS) released its Human Genome Editing Report last week, a wave of questions arose regarding the report's scientific and clinical implications. The report, which outlines criteria that ...
Feb 27, 2017
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Clinical trials for genome editing of the human germline - adding, removing, or replacing DNA base pairs in gametes or early embryos - could be permitted in the future, but only for serious conditions under stringent oversight, ...
Feb 14, 2017
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While many insights are gained into diseases and genetic disorders from rodent models, there is a pressing need to find models that can more accurately represent disease progression in the human body, such as non-human primates. ...
Dec 27, 2016
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CRISPR/Cas9 genome editing is quickly revolutionizing biomedical research, but the new technology is not yet exact. The technique can inadvertently make excessive or unwanted changes in the genome and create off-target mutations, ...
Dec 8, 2016
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While a popular fixture of home aquariums, zebrafish have become a popular and important tool for studying human disease. The fish have more in common with humans than meets the eye, and provide an effective and efficient ...
Jul 29, 2016
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Using gene editing technology, researchers at the Lewis Katz School of Medicine at Temple University have, for the first time, successfully excised a segment of HIV-1 DNA - the virus responsible for AIDS - from the genomes ...
May 19, 2016
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This winter has provided several dramatic developments in the ongoing debate about whether altering the "germline" - that is, the genome of a new embryo - should be allowed. Employing the technique could permanently alter ...
Feb 25, 2016
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(HealthDay)—What if faulty genes in your DNA could be easily corrected, avoiding the ravages of diseases like cystic fibrosis or certain cancers?
Dec 3, 2015
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Researchers led by the Francis Crick institute recently applied to the Human Fertilisation and Embryology Authority for a licence to genetically modify human embryos. The research would use the genome editing technique CRISPR/Cas9 ...
Oct 8, 2015
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