Diseases, Conditions, Syndromes

Methodology from GWAS accurately flags more deadly SARS-CoV-2 variant

Using genome-wide association studies (GWAS) methodology to analyze whole-genome sequencing data of SARS-CoV-2 mutations and COVID-19 mortality data can identify highly pathogenic variants of the virus that should be flagged ...

Diseases, Conditions, Syndromes

Genomic methods aid study of Seattle 2017-2022 Shigella outbreak

A genomic study of a sustained, multidrug-resistant Shigellosis outbreak in Seattle enabled scientists to retrace its origin and spread. Additional analysis of the gut pathogen and its transmission patterns helped direct ...

Genetics

Stretches of repeating DNA predispose to systemic sclerosis

Systemic sclerosis is an autoimmune disorder that is characterized by excess deposition of connective tissue in the skin, lungs, kidneys and vessels, resulting in lung, heart and kidney dysfunction. In a new study, researchers ...

Genetics

New gene variants associated with chronic back pain

Chronic back pain is the number one cause of years lived with disability worldwide. In a new study, Pradeep Suri of the Department of Veterans Affairs in Seattle, Washington, and colleagues in the United States and Europe, ...

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