Genetics

Polygenic risk scores could improve colorectal cancer screening

Rates of colorectal cancer are high despite widespread adoption of screening programs in many high-income European countries. Such programs tend to use a one-size-fits-all approach where most people are screened starting ...

Genetics

Researchers clarify role of blood cell mutations in disease

More than 10% of older adults develop somatic (non-inherited) mutations in blood stem cells that can trigger explosive, clonal expansions of abnormal cells, increasing the risk for blood cancer and cardiovascular disease.

Genetics

Genomic consent: New guideline to help researchers and patients

How can Canada optimize the impact of human genomic sequencing to increase our understanding of disease? New guidance in Canadian Medical Association Journal (CMAJ) lays out the key elements for obtaining patient consent ...

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