More than 10% of older adults develop somatic (non-inherited) mutations in blood stem cells that can trigger explosive, clonal expansions of abnormal cells, increasing the risk for blood cancer and cardiovascular disease.
Feb 8, 2023
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Scientists at St. Jude Children's Research Hospital have created a tool that can find safe places to introduce genes into human DNA. The tool is an early step in the process to improve the safety and efficacy of gene and ...
Sep 22, 2022
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Since COVID-19 emerged, scientists worldwide have sequenced more than 6 million genomes of SARS-CoV-2, the coronavirus behind the disease. Today, the number of SARS-CoV-2 genome sequences exceeds the total number of all other ...
Jul 27, 2022
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A key genetic mutation that occurs early on in cancer alters RNA "dark matter" and causes the release of previously unknown RNA biomarkers for cancer early detection, a new study by UC Santa Cruz researchers published in ...
Jul 19, 2022
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New findings from researchers at Memorial Sloan Kettering Cancer Center (MSK) and published today in the journal Nature Communications report the results of using a comprehensive sequencing approach on 114 pediatric, adolescent, ...
May 18, 2022
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Some rare cases of higher genetic mutation rates in children, known as hypermutation, could be linked to the father receiving certain chemotherapy treatments, new research has found.
May 11, 2022
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UVA Health researchers and their collaborators have developed a better way to predict the risk of chronic obstructive pulmonary disease (COPD), a progressive, potentially deadly form of lung inflammation, for people of non-European ...
May 3, 2022
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In a newly published study appearing in Genetics in Medicine, investigators from Mayo Clinic and Baylor College of Medicine found that targeted genomic information can play an important role in drug prescribing practices.
Mar 22, 2022
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Broad scientists analyzed sequencing data from more than 200,000 people and found rare genetic variants associated with diseases like diabetes and heart failure.
Feb 23, 2022
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Hereditary diseases as well as cancers and cardiovascular diseases may be associated with a phenomenon known as genomic imprinting, in which only the maternally or paternally inherited gene is active. An international research ...
Jan 12, 2022
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