A team of researchers with member affiliations across the U.S. and Canada has found evidence of multiple recurrent, repeat expansions in human cancer genomes. In their paper published in the journal Nature, the group describes ...
Error-prone DNA replication and repair may lead to mutations and cancer in individuals who inherit a mutant copy of the BRCA1 gene, according to a new study by Weill Cornell Medicine investigators. The discovery has potential ...
Nov 15, 2022
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A team of researchers from Weill Cornell Medicine, the British Columbia Cancer Research Centre and Memorial Sloan Kettering Cancer Center, working with a group from the IMAXT Consortium, has used single-cell sequencing to ...
University of Queensland researchers have discovered how COVID-19 damages the heart, opening the door to future treatments.
Sep 30, 2022
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Mutations occur in various tissues and organs of an individual. Somatic mutations occur in cells that will not give rise to offspring and are therefore not passed on to subsequent generations. Caused by a large number of ...
Jul 5, 2022
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The DNA that lies tightly coiled in nearly every human cell is subjected to thousands of insults and injuries from within and without daily, which is why the human body has evolved multiple highly effective mechanisms for ...
Jan 20, 2022
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An international team of researchers has now comprehensively profiled and categorized over 700 tumor samples from patients with chronic lymphocytic leukemia (CLL) by analyzing multiple levels of encoded biologic information.
Dec 6, 2021
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The journal Oncotarget has published "Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal ...
Nov 2, 2021
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The innate human immune system is capable of recognizing and fighting pathogens such as viruses, bacteria or parasites. In addition to other conserved structure, it can detect pathogens based on their RNA and DNA. Since these ...
Oct 5, 2021
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The urgency to remember a dangerous experience requires the brain to make a series of potentially dangerous moves: Neurons and other brain cells snap open their DNA in numerous locations—more than previously realized, according ...
Jul 6, 2021
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