Mutations occur in various tissues and organs of an individual. Somatic mutations occur in cells that will not give rise to offspring and are therefore not passed on to subsequent generations. Caused by a large number of ...
Jul 5, 2022
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294
The DNA that lies tightly coiled in nearly every human cell is subjected to thousands of insults and injuries from within and without daily, which is why the human body has evolved multiple highly effective mechanisms for ...
Jan 20, 2022
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63
An international team of researchers has now comprehensively profiled and categorized over 700 tumor samples from patients with chronic lymphocytic leukemia (CLL) by analyzing multiple levels of encoded biologic information.
Dec 6, 2021
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5
The journal Oncotarget has published "Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal ...
Nov 2, 2021
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The innate human immune system is capable of recognizing and fighting pathogens such as viruses, bacteria or parasites. In addition to other conserved structure, it can detect pathogens based on their RNA and DNA. Since these ...
Oct 5, 2021
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68
The urgency to remember a dangerous experience requires the brain to make a series of potentially dangerous moves: Neurons and other brain cells snap open their DNA in numerous locations—more than previously realized, according ...
Jul 6, 2021
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360
Tousled-like kinases (TLKs) are a potential therapeutic target for cancer treatment due to their central role in DNA repair and replication. The latest work by IRB Barcelona's Genomic Instability and Cancer Laboratory, led ...
Aug 5, 2020
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Researchers at the Karolinska Institutet have discovered a new interaction between two proteins that reduce the risk of DNA damage and cellular cancer development. The findings on the proteins RTEL1 and Poldip3 are published ...
Jun 18, 2020
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A new University of California, Irvine-led study reveals a protein responsible for genetic changes resulting in a variety of cancers, may also be the key to more effective, targeted cancer therapy.
Jun 12, 2020
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83
Two genes that appear to help stem cells in the intestine burn dietary fat may play a role in colon cancer, according to a Rutgers study.
Nov 25, 2019
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