The master regulator behind the development of antibody-producing cells has been identified in a study by investigators at Weill Cornell Medicine. The findings provide new insight into the inner workings of the immune system ...
Sep 23, 2021
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When we are exposed to a pathogen, the immune system's B cells swarm to our lymph nodes, spleens, and tonsils. There, those cells mutate in germinal centers—microscopic boot camps that rush the B cells through volleys of ...
Jul 16, 2021
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No story in biology is more intriguing than the one involving B cells and the intricate processes that result in antibody production—it's a story about mathematics, a tale of genetics and a saga of how vast armies of tiny ...
The gut is an unusually noisy place, where hundreds of species of bacteria live alongside whatever microbes happen to have hitched a ride in on your lunch. Scientists have long suspected that the gut's immune system, in the ...
Oct 29, 2020
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Shiv Pillai, MD, Ph.D., investigator in the Ragon Institute of MGH, MIT and Harvard and professor at Harvard Medical School (HMS), recently published a paper in Cell showing that high levels of some cytokines seen in COVID-19 ...
Aug 20, 2020
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The release of massive amounts of proteins called cytokines can lead to some of the most severe symptoms of COVID-19. When large numbers of immune cells release cytokines, this increases inflammation and creates a feedback ...
Aug 19, 2020
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Every year, we're reminded to return to the pharmacy for a flu shot. Why can't we have a flu vaccine that offers long-term protection, like those for measles or polio? That's because the influenza virus continuously evolves, ...
Dec 20, 2019
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A new HIV vaccine delivery strategy appears to enhance the protective immune response in a preclinical model. Scientists at the La Jolla Institute for Immunology (LJI) have discovered that delivering an HIV vaccine in small ...
May 9, 2019
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Plasma B cells, which move through the body releasing antibodies, are an important component of the body's fight against viral infections and other invaders. They are relatively rare, however, and increasing their ranks is ...
Apr 18, 2018
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When we encounter a pathogen, the immune system is usually able to respond quickly and forcefully to protect us from infection. Some of its preparedness is inherent in the process by which white blood cells called B cells ...
Jan 11, 2018
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