Immunology

How the immune system deals with the gut's plethora of microbes

The gut is an unusually noisy place, where hundreds of species of bacteria live alongside whatever microbes happen to have hitched a ride in on your lunch. Scientists have long suspected that the gut's immune system, in the ...

Diseases, Conditions, Syndromes

COVID-19 cytokine storms may prevent a durable immune response

Shiv Pillai, MD, Ph.D., investigator in the Ragon Institute of MGH, MIT and Harvard and professor at Harvard Medical School (HMS), recently published a paper in Cell showing that high levels of some cytokines seen in COVID-19 ...

Medical research

New clues about why a universal flu vaccine is so elusive

Every year, we're reminded to return to the pharmacy for a flu shot. Why can't we have a flu vaccine that offers long-term protection, like those for measles or polio? That's because the influenza virus continuously evolves, ...

HIV & AIDS

New HIV vaccine strategy 'pumps' the immune system

A new HIV vaccine delivery strategy appears to enhance the protective immune response in a preclinical model. Scientists at the La Jolla Institute for Immunology (LJI) have discovered that delivering an HIV vaccine in small ...

Immunology

Researchers uncover origin of virus-fighting plasma B cells

Plasma B cells, which move through the body releasing antibodies, are an important component of the body's fight against viral infections and other invaders. They are relatively rare, however, and increasing their ranks is ...

Immunology

How the immune system curbs its own mistakes

When we encounter a pathogen, the immune system is usually able to respond quickly and forcefully to protect us from infection. Some of its preparedness is inherent in the process by which white blood cells called B cells ...

Immunology

Modulating immune responses

The protein Roquin plays a key role in the regulation of immune reactions. LMU researchers have now uncovered details of the mechanism by which it controls the function of regulatory T cells in the adaptive arm of the immune ...

Immunology

Finding what fuels the 'runaway train' of autoimmune disease

A newly-unveiled discovery, which has been four years in the making, has the potential to change the way we look at autoimmune diseases and understand how and why immune cells begin to attack different tissues in the body.

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